Medetomidine HCl 3.3 mg/mL + Ketamine HCl 150 mg/mL + Midazolam HCl 5 mg/mL, Injectable Solution, 10mL

• Overview of the Solution: Medetomidine HCl 3.3 mg/mL + Ketamine HCl 150 mg/mL + Midazolam HCl 5 mg/mL is a potent combination used in veterinary anesthesia.
• Relevance in Veterinary Medicine: Essential for ensuring animal welfare during surgical and diagnostic procedures.
• Purpose of the Article: To provide detailed insights into the composition, applications, benefits, risks, and best practices for this injectable solution.

Composition and Mechanism of Action

• Medetomidine Hydrochloride (3.3 mg/mL)
  • Alpha-2 adrenergic agonist.
  • Mechanism: Reduces sympathetic outflow, leading to sedation and analgesia.
• Ketamine Hydrochloride (150 mg/mL)
  • NMDA receptor antagonist.
  • Mechanism: Induces dissociative anesthesia, analgesia, and amnesia.
• Midazolam Hydrochloride (5 mg/mL)
  • Benzodiazepine.
  • Mechanism: Enhances GABAergic transmission, causing sedation, anxiolysis, and muscle relaxation.